Gallamine
Gallamine is a non-depolarizing muscle relaxant. It acts by blocking the effects of acetylcholine at the neuromuscular junction. Gallamine has a tri-ethiodide ion, which is responsible for its muscle relaxant properties.
Pharmacology[edit | edit source]
Gallamine works by binding to the acetylcholine receptors at the neuromuscular junction, thereby inhibiting the action of acetylcholine. This results in muscle relaxation. The drug has a rapid onset of action and a short duration of effect.
Uses[edit | edit source]
Gallamine is used in anesthesia to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Side Effects[edit | edit source]
Possible side effects of gallamine include hypotension, tachycardia, and increased salivation. It may also cause an increase in intraocular pressure, making it unsuitable for use in patients with glaucoma.
Contraindications[edit | edit source]
Gallamine is contraindicated in patients with known hypersensitivity to the drug. It should also be used with caution in patients with myasthenia gravis, as it may exacerbate the condition.
Interactions[edit | edit source]
Gallamine may interact with other drugs such as antibiotics, calcium channel blockers, and magnesium sulfate, which may enhance its neuromuscular blocking effects.
See Also[edit | edit source]
Gallamine Resources | ||
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