Hashimoto’s disease

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Hashimoto’s disease, also known as Hashimoto’s thyroiditis, is an autoimmune disorder that affects the thyroid gland. It is named after the Japanese physician Hakaru Hashimoto, who first described the condition in 1912. Hashimoto’s disease is the most common cause of hypothyroidism, a condition in which the thyroid gland does not produce enough thyroid hormones.

Symptoms[edit | edit source]

The symptoms of Hashimoto’s disease can vary widely and may include fatigue, weight gain, constipation, dry skin, hair loss, sensitivity to cold, muscle weakness, and depression. Some individuals may also experience a goiter, which is an enlargement of the thyroid gland.

Causes[edit | edit source]

Hashimoto’s disease occurs when the immune system mistakenly attacks the thyroid gland, leading to inflammation and damage. The exact cause of this autoimmune response is not fully understood, but it is believed to involve a combination of genetic and environmental factors.

Diagnosis[edit | edit source]

Diagnosis of Hashimoto’s disease typically involves a physical examination, blood tests to measure levels of thyroid hormones and antibodies, and imaging studies such as ultrasound of the thyroid gland. A biopsy of the thyroid gland may also be performed in some cases.

Treatment[edit | edit source]

Treatment for Hashimoto’s disease usually involves thyroid hormone replacement therapy to restore normal hormone levels. This may help alleviate symptoms and prevent complications associated with hypothyroidism. In some cases, anti-inflammatory medications may be prescribed to reduce inflammation in the thyroid gland.

Prognosis[edit | edit source]

With proper treatment, most individuals with Hashimoto’s disease can lead normal, healthy lives. However, regular monitoring of thyroid function and medication adjustments may be necessary to manage the condition effectively.


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Contributors: Prab R. Tumpati, MD