Heptabarbital

From WikiMD's Food, Medicine & Wellness Encyclopedia

Heptabarbital is a barbiturate derivative that was first synthesized in the 1920s. It is primarily used as a sedative and hypnotic drug in the treatment of insomnia and other sleep disorders. Heptabarbital is also used in some cases for the treatment of anxiety and seizure disorders.

Pharmacology[edit | edit source]

Heptabarbital, like other barbiturates, works by increasing the activity of the gamma-aminobutyric acid (GABA) neurotransmitter in the brain. GABA is an inhibitory neurotransmitter, meaning it reduces the activity of the neurons to which it binds. By enhancing the effects of GABA, heptabarbital helps to calm the brain and induce sleep.

Side Effects[edit | edit source]

Common side effects of heptabarbital include drowsiness, dizziness, and impaired coordination. More serious side effects can include respiratory depression, addiction, and, in rare cases, death. Due to the risk of addiction and overdose, heptabarbital is typically only prescribed for short-term use.

History[edit | edit source]

Heptabarbital was first synthesized in the 1920s as part of a series of barbiturate derivatives. It was widely used throughout the mid-20th century, but its use has declined in recent years due to the development of safer and more effective sleep aids.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD