List of progestogens
Progestogens are a type of steroid hormone that bind to and activate the progesterone receptor. They play a key role in the menstrual cycle and pregnancy. This article provides a list of progestogens, which are classified into generations based on their time of introduction and structural similarity.
First Generation Progestogens[edit | edit source]
The first generation progestogens include progesterone and its derivatives. They are structurally similar to the natural hormone progesterone.
- Progesterone: It is a natural hormone involved in the menstrual cycle, pregnancy, and embryogenesis.
- Medroxyprogesterone acetate: It is a derivative of progesterone and is used in hormonal contraception and hormone therapy.
Second Generation Progestogens[edit | edit source]
The second generation progestogens are derivatives of 19-nortestosterone. They have enhanced potency and reduced androgenic activity.
- Norethisterone: It is a synthetic progestogen used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders.
- Levonorgestrel: It is used in emergency contraception, intrauterine devices, contraceptive implants, and combined oral contraceptives.
Third Generation Progestogens[edit | edit source]
The third generation progestogens have improved pharmacokinetics and reduced side effects.
- Desogestrel: It is used in contraceptive pills and has less androgenic effects.
- Gestodene: It is used in contraceptive pills and has less androgenic and metabolic effects.
Fourth Generation Progestogens[edit | edit source]
The fourth generation progestogens have selective progesterone receptor modulator activity.
- Drospirenone: It is used in contraceptive pills and has antiandrogenic and antimineralocorticoid effects.
- Dienogest: It is used in contraceptive pills and for the treatment of endometriosis.
See Also[edit | edit source]
- Progesterone receptor
- Menstrual cycle
- Pregnancy
- Steroid hormone
- Hormonal contraception
- Hormone therapy
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