List of psychoactive drugs used by militaries

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List of Psychoactive Drugs Used by Militaries

The use of psychoactive drugs by militaries is a practice that spans across various cultures and epochs. These substances, which alter perception, mood, consciousness, cognition, or behavior, have been utilized for their performance-enhancing, therapeutic, and recreational properties. This article provides an overview of notable psychoactive drugs that have been reported to be used by military forces around the world.

Stimulants[edit | edit source]

Stimulants are drugs that increase alertness, attention, and energy. They are often used in military contexts to combat fatigue, enhance endurance, and improve focus during extended operations.

  • Amphetamine: Widely used during World War II by several countries to maintain alertness and delay fatigue among soldiers. It continues to be used in certain military operations to sustain wakefulness.
  • Modafinil: A newer stimulant with fewer side effects compared to amphetamines. It is used by some air forces, including the United States Air Force, to help pilots remain alert during long missions.
  • Caffeine: Perhaps the most commonly used psychoactive substance, caffeine is consumed in various forms (coffee, tea, energy drinks) to enhance alertness and performance.

Sedatives and Hypnotics[edit | edit source]

These substances are used to induce sleep or reduce anxiety in situations where rest is crucial but difficult to achieve due to stress or environmental factors.

  • Benzodiazepines: Used for their anxiolytic and hypnotic effects, particularly in scenarios involving high stress or the need to rest in preparation for operations.
  • Zolpidem: A short-acting hypnotic prescribed to manage insomnia, including in military contexts where rapid sleep onset is necessary.

Analgesics[edit | edit source]

Pain management is critical in military medicine, both on and off the battlefield. Analgesics are used to alleviate pain, allowing soldiers to continue their mission or recover from injuries.

  • Morphine: A potent opiate used for severe pain, often administered in emergency situations or in combat casualty care.
  • Ketamine: Initially used as an anesthetic, ketamine has been employed for its analgesic and antidepressant effects, particularly in treating chronic pain and post-traumatic stress disorder (PTSD) among veterans.

Performance Enhancers[edit | edit source]

In addition to stimulants, other substances are used to enhance physical and cognitive performance.

  • Anabolic steroids: Synthetic substances similar to the male sex hormone testosterone. They are sometimes used to increase muscle mass and strength.
  • Erythropoietin (EPO): A hormone used to increase red blood cell count, enhancing oxygen delivery to muscles and improving endurance.

Psychedelics[edit | edit source]

Psychedelics have been researched for various applications, including as potential tools for psychological warfare or to treat mental health conditions among veterans.

  • LSD (Lysergic acid diethylamide): Investigated by the CIA under Project MKUltra for its potential use in mind control and chemical warfare, though not operationally deployed.
  • MDMA (Ecstasy): Currently under research for its potential to assist in treating PTSD among military personnel and veterans.

Challenges and Controversies[edit | edit source]

The use of psychoactive drugs in military contexts raises ethical, legal, and health-related concerns. Issues such as dependency, long-term health effects, consent, and the potential for abuse are subjects of ongoing debate.

This list is incomplete; you can help WikiMD by expanding it.


The use of psychoactive substances by militaries is a complex topic, influenced by medical, ethical, and tactical considerations. As research continues and the nature of warfare evolves, the list of substances and their applications may change.

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Contributors: Prab R. Tumpati, MD