MT-TE
MT-TE or Mitochondrial tRNA Threonine is a gene that in humans is encoded by the MT-TE genetic sequence. This gene is a member of the mitochondrial DNA (mtDNA) tRNA family and plays a crucial role in the protein synthesis within the mitochondria.
Function[edit | edit source]
The MT-TE gene provides instructions for making a molecule called transfer RNA (tRNA) which is essential for assembling amino acids into functioning proteins. Specifically, the MT-TE gene produces a tRNA molecule that helps incorporate the amino acid threonine into proteins. This process is a critical part of the mitochondrial protein synthesis.
Clinical significance[edit | edit source]
Mutations in the MT-TE gene have been associated with several mitochondrial disorders, including Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) and Myoclonic Epilepsy with Ragged Red Fibers (MERRF). These conditions often involve muscle weakness and pain, seizures, and problems with movement and balance.
See also[edit | edit source]
References[edit | edit source]
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