Monohybrid cross

Monohybrid Cross

A Monohybrid Cross is a fundamental concept in genetics, specifically in the study of Mendelian inheritance. It refers to a cross between two individuals with different variations at one genetic chromosomal locus. The term "monohybrid" is derived from "mono" meaning one, and "hybrid" indicating a mix of genetic material. This method of genetic study was first utilized by Gregor Mendel in his pioneering work on pea plants.

Overview

A monohybrid cross involves the crossing of individuals, often of the same species, that differ in a single given trait. The trait in question is typically determined by a single gene with two different alleles. The resulting offspring, or F1 generation, are then observed for the expression of the trait.

Mendel's Experiments

Gregor Mendel, an Austrian monk, is often referred to as the "father of genetics" due to his significant contributions to the field. His experiments with pea plants in the mid-19th century laid the foundation for the understanding of genetic inheritance. Mendel's monohybrid cross experiments involved traits such as seed color and plant height. His observations led to the formulation of the laws of inheritance.

Punnett Square

The Punnett square is a diagrammatic tool used in the study of monohybrid crosses. Named after its creator, British geneticist Reginald Punnett, it provides a visual representation of possible genetic combinations in the offspring. The Punnett square is a fundamental tool in understanding the principles of dominance, recessiveness, and probability in genetics.

Genotypic and Phenotypic Ratios

In a monohybrid cross, the genotypic and phenotypic ratios of the offspring can be predicted. The genotypic ratio refers to the ratio of the different genotypes that could appear in offspring, while the phenotypic ratio refers to the ratio of the different physical characteristics that could appear.

See Also

• Dihybrid cross
• Test cross
• Backcross
• Genetic linkage