NAN-190

NAN-190

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NAN-190 is a chemical compound that acts as a selective antagonist of the 5-HT1A receptor. It is commonly used in scientific research to study the role of the 5-HT1A receptor in various physiological and neurological processes.

Chemical Properties

NAN-190 has the chemical formula C19H23N3O2 and a molecular weight of 325.41 g/mol. It is a member of the piperazine class of compounds and is structurally related to other 5-HT1A receptor antagonists.

Pharmacology

NAN-190 is known for its high affinity and selectivity for the 5-HT1A receptor, a subtype of the serotonin receptor family. By binding to this receptor, NAN-190 inhibits the action of serotonin, a neurotransmitter involved in mood regulation, anxiety, and other central nervous system functions.

Research Applications

NAN-190 is widely used in neuroscience research to investigate the role of the 5-HT1A receptor in various conditions, including depression, anxiety disorders, and schizophrenia. It is also used to study the receptor's involvement in cognitive function and memory.

Mechanism of Action

As a 5-HT1A receptor antagonist, NAN-190 blocks the receptor's activity, preventing serotonin from exerting its effects. This blockade can help researchers understand the physiological and behavioral outcomes associated with 5-HT1A receptor activity.

Safety and Handling

NAN-190 should be handled with care in a laboratory setting. Appropriate safety measures, including the use of personal protective equipment (PPE), should be followed to avoid exposure.

See Also

• 5-HT1A receptor
• Serotonin
• Neurotransmitter
• Piperazine

References

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