PTK787/ZK 222584

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PTK787/ZK 222584 (also known as vatalanib) is a type of drug that is used in the treatment of cancer. It is a small molecule tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor (VEGFR) and platelet-derived growth factor receptor (PDGFR).

Mechanism of Action[edit | edit source]

PTK787/ZK 222584 works by inhibiting the activity of certain proteins that are involved in the growth and spread of cancer cells. These proteins include VEGFR and PDGFR, which are both types of tyrosine kinases. By blocking these proteins, PTK787/ZK 222584 can help to slow down the growth of cancer cells and prevent them from spreading to other parts of the body.

Clinical Trials[edit | edit source]

Several clinical trials have been conducted to evaluate the effectiveness of PTK787/ZK 222584 in treating various types of cancer. These trials have shown that the drug can be effective in some cases, but further research is needed to determine the best ways to use it in clinical practice.

Side Effects[edit | edit source]

Like all drugs, PTK787/ZK 222584 can cause side effects. These can vary from person to person, but may include nausea, vomiting, diarrhea, and fatigue. If you are taking this drug and experience any unusual symptoms, it is important to contact your doctor right away.

See Also[edit | edit source]

PTK787/ZK 222584 Resources
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Contributors: Prab R. Tumpati, MD