S-Methylmethionine
S-Methylmethionine (also known as Vitamin U) is a derivative of methionine which is found in various plant species. It was first isolated in 1949 by Garnett and co-workers from cabbage juice, where it was shown to have a protective effect on peptic ulcers in humans.
Chemistry[edit | edit source]
S-Methylmethionine is a quaternary ammonium salt that is structurally similar to the amino acid methionine, except that the alpha-hydrogen is replaced by a methyl group. It is synthesized in plants from methionine and S-adenosyl methionine (SAM) via the Yang cycle.
Biological role[edit | edit source]
In plants, S-Methylmethionine acts as a methyl donor in a variety of methylation reactions. It is also involved in the synthesis of ethylene, a plant hormone that regulates growth and development.
In humans, S-Methylmethionine has been shown to have a protective effect on the gastrointestinal tract, particularly in the prevention and treatment of peptic ulcers. However, its exact mechanism of action is still not fully understood.
Sources[edit | edit source]
S-Methylmethionine is found in a variety of plant species, including cabbage, spinach, and alfalfa. It is also available as a dietary supplement.
Safety[edit | edit source]
S-Methylmethionine is generally considered safe when consumed in amounts typically found in food. However, excessive intake may cause mild gastrointestinal symptoms such as nausea and diarrhea.
See also[edit | edit source]
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