Uterine involution

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Uterine involution is the process by which the uterus returns to its pre-pregnancy size and condition after childbirth. This process begins immediately after the delivery of the placenta and continues for several weeks.

Physiology[edit | edit source]

During pregnancy, the uterus undergoes significant changes to accommodate the growing fetus. These changes include an increase in size, weight, and capacity. After childbirth, the uterus begins to contract and shrink back to its pre-pregnancy state, a process known as uterine involution.

The process of uterine involution involves several physiological changes. These include the reduction in the size of the uterus, the shedding of the endometrium (the lining of the uterus), and the regeneration of the endometrium. The process is facilitated by the hormone oxytocin, which is released during and after childbirth.

Stages of Uterine Involution[edit | edit source]

Uterine involution can be divided into three stages:

  1. Immediate Involution (First 24 hours): This stage begins immediately after the delivery of the placenta. The uterus contracts to control bleeding and to expel any remaining placental tissue.
  2. Early Involution (First 10 days): During this stage, the uterus continues to contract and decrease in size. The endometrium begins to shed and regenerate.
  3. Late Involution (Up to 6 weeks): In this final stage, the uterus returns to its pre-pregnancy size and position. The endometrium is fully regenerated.

Clinical Significance[edit | edit source]

Understanding the process of uterine involution is important in the clinical setting as it can help healthcare providers identify potential complications after childbirth. These can include postpartum hemorrhage, endometritis, and uterine subinvolution (a condition where the uterus does not return to its pre-pregnancy size).

See Also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD