Amanitins

Alpha-amanitin-Ball-and-Stick-Animation

What are amaninitins?

Amaninitis are cyclic peptides extracted from carpophores of various mushroom species.

Amanita flavipes

Use in molecular genetics

They are potent inhibitors of RNA polymerases in most eukaryotic species, blocking the production of mRNA and protein synthesis.

Study of transcription

These peptides are important in the study of transcription.

Types

There are 4 main types of amanitins, of which α-Amanitin is the most popular. α-Amanitin β-Amanitin γ-Amanitin ε-Amanitin

Mushroom poisoning

Alpha-amanitin is the main toxin from the species Amanitia phalloides, poisonous if ingested by humans or animals.

Amanitins Resources
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