Amyloid plaque
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- The sticky, abnormal accumulations of amyloid-beta protein aggregate around neuronsand synapses in the memory and intellectual centers of the brain, in people with Alzheimer’s. These aresometimes referred to as neuritic plaques or senile plaques. While amyloid plaques have long beenconsidered markers of Alzheimer’s, they are also found to some extent in many cognitively normalelderly people. Plaques’ role in Alzheimer’s neurodegeneration remains unclear.
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Contributors: Prab R. Tumpati, MD
