Carbon-13

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Carbon-13[edit | edit source]

Carbon-13 is an isotope of carbon with a nucleus containing 6 protons and 7 neutrons.

Carbon-13 is a stable isotope of the element carbon. It is represented by the symbol ^13C, indicating that it has an atomic mass of 13. Carbon-13 makes up about 1.1% of all carbon atoms found in nature, with the remaining 98.9% being the more common isotope, carbon-12 (^12C).

Discovery and Properties[edit | edit source]

Carbon-13 was first discovered in 1934 by the American chemist Martin Kamen. He used a mass spectrometer to separate the different isotopes of carbon based on their mass-to-charge ratio. This groundbreaking technique allowed scientists to study the isotopic composition of various elements in greater detail.

The nucleus of carbon-13 contains 6 protons and 7 neutrons, giving it an atomic mass of 13 atomic mass units. This is slightly higher than the atomic mass of carbon-12, which has 6 protons and 6 neutrons. The extra neutron in carbon-13 makes it slightly heavier and less abundant in nature.

Applications[edit | edit source]

Carbon-13 has several important applications in various fields of science:

1. Carbon Dating: One of the most well-known applications of carbon-13 is in radiocarbon dating. By measuring the ratio of carbon-13 to carbon-12 in organic materials, scientists can determine the age of ancient artifacts and fossils. This technique relies on the fact that the ratio of carbon-13 to carbon-12 in the atmosphere has remained relatively constant over time.

2. Nuclear Magnetic Resonance (NMR): Carbon-13 NMR spectroscopy is a powerful analytical technique used in chemistry and biochemistry. By analyzing the signals produced by carbon-13 nuclei in a sample, scientists can determine the structure and composition of organic molecules. This technique provides valuable insights into the molecular structure of compounds, aiding in drug discovery, materials science, and other fields.

3. Isotope Labeling: Carbon-13 is often used as a tracer in scientific research. By incorporating carbon-13 into molecules of interest, scientists can track the movement and transformation of these molecules in biological systems. This technique is particularly useful in studying metabolic pathways, protein interactions, and drug metabolism.

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD