Continuous hyperthermic peritoneal perfusion

From WikiMD's Food, Medicine & Wellness Encyclopedia

Continuous Hyperthermic Peritoneal Perfusion (CHPP) is a type of hyperthermia therapy used to treat peritoneal carcinomatosis, a condition where cancer has spread to the lining of the abdomen.

Procedure[edit | edit source]

In CHPP, the abdomen is heated to a high temperature and filled with a chemotherapy solution. This is done to kill cancer cells that may be in the abdomen. The solution is circulated continuously for 1 to 2 hours and then drained.

Uses[edit | edit source]

CHPP is used to treat peritoneal carcinomatosis from colorectal cancer, appendix cancer, stomach cancer, ovarian cancer, mesothelioma, and primary peritoneal carcinoma.

Benefits[edit | edit source]

The benefits of CHPP include the ability to deliver high doses of chemotherapy directly to the cancer cells in the abdomen, while minimizing the amount of drug that reaches the rest of the body. This can reduce side effects and increase the effectiveness of the treatment.

Risks[edit | edit source]

The risks of CHPP include infection, bleeding, damage to the intestines or other organs, and side effects from the chemotherapy drugs.

Alternatives[edit | edit source]

Alternatives to CHPP include systemic chemotherapy, radiation therapy, and surgery. The choice of treatment depends on the type and stage of the cancer, the patient's overall health, and the patient's preferences.

See Also[edit | edit source]

Continuous hyperthermic peritoneal perfusion Resources
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Contributors: Prab R. Tumpati, MD