Cyclic citrullinated peptide
Cyclic citrullinated peptide antibodies, or CCP antibodies, are a type of antibody called autoantibodies.
What are autoantibodies?[edit | edit source]
Antibodies and autoantibodies are proteins made by the immune system.
CCP antibody test[edit | edit source]
CCP antibodies target healthy tissues in the joints and hence presence of CCP antibodies can be a sign of rheumatoid arthritis.
Other names[edit | edit source]
Cyclic citrullinated peptide antibody, anticitrullinated peptide antibody, citrulline antibody, anti-cyclic citrullinated peptide, anti-CCP antibody, ACPA
Other tests[edit | edit source]
Another test that is commonly performed in the diagnostic evaluation of rheumatoid arthritis is rheumatoid factor (RF) test as well as a physical exam
Interpreting CCP test rests[edit | edit source]
CCP test results are interpreted along with RF test and clinical presentation.
- Positive CCP antibodies and positive RF, it likely means that you have rheumatoid arthritis.
- Positive CCP antibodies and negative RF, it may mean you are in the early stages of rheumatoid arthritis or will develop it in the future.
- Negative CCP antibodies and negative RF, it means you are less likely to have rheumatoid arthritis.
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