Dermal papilla

From WikiMD's Food, Medicine & Wellness Encyclopedia

Dermal Papilla is a small, nipple-like extension (or protrusion) of the dermis layer of the skin. Dermal papillae are found in the superficial layer of the dermis, known as the papillary dermis, and extend into the epidermis, the outermost layer of the skin.

Structure[edit | edit source]

Dermal papillae are composed of connective tissues and cells, which include fibroblasts, macrophages, and adipocytes. They are rich in capillaries and nerves, which supply nutrients and sensory information to the epidermis.

Function[edit | edit source]

The primary function of dermal papillae is to anchor the epidermis to the dermis and provide it with nutrients. They also play a crucial role in temperature regulation and tactile sensation. In addition, dermal papillae are involved in the formation of fingerprints and footprints, contributing to the unique patterns on the skin's surface.

Clinical Significance[edit | edit source]

Abnormalities in the structure or function of dermal papilla can lead to various skin conditions, such as psoriasis, alopecia, and vitiligo. Research is ongoing to understand the role of dermal papillae in these conditions and develop effective treatments.

See Also[edit | edit source]

Dermal papilla Resources
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Contributors: Prab R. Tumpati, MD