Ependymal cell

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Ependymal cells are a type of neuroglia that line the ventricles of the brain and the central canal of the spinal cord. They are involved in the production and circulation of cerebrospinal fluid (CSF).

Function[edit | edit source]

Ependymal cells are responsible for the production of a portion of the cerebrospinal fluid (CSF), which is a clear, colorless body fluid found in the brain and spinal cord. They also aid in the circulation of CSF, which acts as a cushion or buffer for the brain, providing basic mechanical and immunological protection to the brain inside the skull.

Structure[edit | edit source]

Ependymal cells are one of the four main types of neuroglia in the central nervous system. They are epithelial cells that line the ventricles in the brain and the central canal of the spinal cord. These cells are characterized by their cilia and microvilli that extend into the ventricular system.

Clinical significance[edit | edit source]

Abnormalities or damage to ependymal cells can lead to a number of medical conditions. For example, hydrocephalus can occur if the flow of CSF is blocked. This can be due to a lack of cilia on the ependymal cells, preventing the proper circulation of CSF. Ependymal cells can also give rise to certain types of brain tumors, known as ependymomas.

See also[edit | edit source]

Ependymal cell Resources
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Contributors: Prab R. Tumpati, MD