Ethylol

Ethylol is a medication used in the treatment of various medical conditions. It is also known by its generic name, Amifostine. This drug is classified as a cytoprotective agent, which means it helps protect normal cells from damage during cancer treatments.

Uses

Ethylol is primarily used to reduce the side effects of radiation therapy and chemotherapy in cancer patients. It is particularly effective in reducing the risk of xerostomia (dry mouth) in patients undergoing radiation treatment for head and neck cancer. Ethylol can also help protect the kidneys from the harmful effects of certain chemotherapy drugs.

Mechanism of Action

Ethylol works by selectively protecting normal tissues from the harmful effects of radiation therapy and chemotherapy. It does this by scavenging free radicals and by increasing the production of certain protective enzymes in normal cells.

Side Effects

Like all medications, Ethylol can cause side effects. Common side effects include nausea, vomiting, and hypotension (low blood pressure). In rare cases, Ethylol can cause severe allergic reactions.

Dosage and Administration

Ethylol is administered by intravenous infusion, usually 15 to 30 minutes before radiation therapy or chemotherapy. The dosage is based on the patient's body surface area.

Precautions

Before starting treatment with Ethylol, patients should inform their doctor about any other medications they are taking, as Ethylol can interact with other drugs. Patients should also inform their doctor if they have any allergies or medical conditions, especially kidney disease, heart disease, or blood pressure problems.

See Also

• Chemotherapy
• Radiation Therapy
• Cancer
• Xerostomia

References

• National Cancer Institute
• American Cancer Society

Ethylol Resources
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