Evidence-based toxicology
Evidence-based toxicology (EBT) is a discipline that applies the principles and methods of evidence-based medicine to the field of toxicology. It aims to transparently, consistently, and objectively assess available scientific evidence in order to answer questions in toxicology.
History[edit | edit source]
The concept of EBT was first proposed in 2006 by a group of toxicologists and systematic review experts. The idea was to apply the principles of evidence-based medicine to toxicology, in order to improve the transparency, consistency, and objectivity of assessments in the field.
Principles[edit | edit source]
EBT is based on the following principles:
- Transparency in the process of assessment
- Consistency in the application of criteria
- Objectivity in the interpretation of evidence
These principles are applied through the use of systematic review methods, which involve a structured and documented process for identifying, selecting, and appraising relevant studies.
Applications[edit | edit source]
EBT can be applied in various areas of toxicology, including:
- Risk assessment
- Regulatory toxicology
- Forensic toxicology
- Clinical toxicology
- Environmental toxicology
Challenges[edit | edit source]
Despite its potential benefits, the implementation of EBT faces several challenges. These include the need for training in systematic review methods, the need for more high-quality studies in toxicology, and the need for tools and resources to facilitate the application of EBT.
Future Directions[edit | edit source]
The future of EBT lies in the continued development and refinement of systematic review methods for toxicology, as well as in the integration of these methods into regulatory decision-making processes.
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Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.Contributors: Prab R. Tumpati, MD