Fluoroplex

What is Fluoroplex?[edit | edit source]

Fluoroplex (Fluorouracil (Topical)) is an antineoplastic/antimetabolite product used as a cream to treat actinic keratosis (a skin condition that may become cancer).

Fluorouracil

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Fluoroplex (Fluorouracil (Topical)) cream is a prescription medicine used on the skin to treat multiple actinic (solar) keratosis.

Fluorouracil mechanism

Fluorouracil (or its metabolites) blocks the methylation reaction of deoxyuridylic acid to thymidylic acid.
In this fashion, fluorouracil interferes with the synthesis of deoxyribonucleic acid (DNA) and to a lesser extent inhibits the formation of ribonucleic acid (RNA).

This medicine cannot be used in patients:

Tell your doctor about all medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of them and show it to your doctor and pharmacist each time you get a new medicine.
Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

Recommended dosage:

Apply medication twice daily with fingertips and wash hands afterwards.
A treatment period of 2-6 weeks is usually required.
Increasing the frequency of application and a longer period of administration with Fluoroplex Cream may be required on areas other than the head and neck.

Administration:

Fluoroplex Cream is usually applied 2 times a day for 2 to 6 weeks.
Use your fingertips to apply enough Fluoroplex Cream to cover the areas to be treated on your face or other affected areas, as instructed by your healthcare provider.
Skin reactions are expected when you use Fluoroplex Cream. These skin reactions begin with redness, usually followed by dryness or tenderness and crusting of your skin. Before you see any healing of your skin, these skin reactions continue to progress. Stop using Fluoroplex Cream when you see raw areas (erosion and ulcers) and shedding of dead skin (sloughing). Be sure to follow your healthcare provider’s instructions about when to stop using Fluoroplex Cream.
If your skin reaction bothers you or is severe, or if you are not sure what to do, call your healthcare provider for instructions.
Avoid letting Fluoroplex Cream build up in the skin folds around your eyes, nose or mouth.
Wash your hands right away after you apply Fluoroplex Cream. If you accidentally get Fluoroplex Cream in your eyes, flush your eyes with water or normal saline.

This medicine is available in fallowing doasage form:

This medicine is available in fallowing brand namesː

The most common side effects of this medicine include:

The patient should avoid prolonged exposure to sunlight or other forms of ultraviolet irradiation during treatment with Fluoroplex Cream, as the intensity of the reaction may be increased.
There is a possibility of increased absorption through ulcerated or inflamed skin.
The medication should be applied with care near the eyes, nose, and mouth. Excessive reaction in these areas may occur due to irritation from accumulation of drug.
Fluorouracil, including Fluoroplex Cream may be fatal if ingested by pets. Avoid allowing pets to contact the Fluoroplex Cream container or the skin where Fluoroplex® Cream has been applied.
Fluorouracil may cause fetal harm when administered to a pregnant woman. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to the fetus.

Symptoms of overdosage may include:

Overdosage will not cause acute problems.
If Fluoroplex Cream accidentally comes in contact with the eye(s), flush the eyes(s) with water or normal saline.

Management of overdosage:

Active ingredient: fluorouracil
Inactive ingredients: benzyl alcohol, emulsifying wax, isopropyl myristate, mineral oil, purified water, and sodium hydroxide.

Manufactured by:

Fluoroplex Resources
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