Hemophilia b
Hemophilia B is a genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding. This results in people bleeding longer after an injury, easy bruising, and an increased risk of bleeding inside joints or the brain.
Causes[edit | edit source]
Hemophilia B is caused by a deficiency of factor IX, a clotting protein. It is inherited in an X-linked recessive pattern, meaning that the gene causing the condition is located on the X chromosome. Males are affected by X-linked recessive disorders much more frequently than females.
Symptoms[edit | edit source]
The symptoms of Hemophilia B can vary greatly depending on the severity of the factor IX deficiency. Common symptoms include:
- Bleeding into muscles and joints, such as the knees, elbows, and ankles
- Spontaneous bleeding
- Prolonged bleeding from cuts, tooth extraction, and surgery
- Easy bruising
- Blood in urine or stool
- Nosebleeds
Diagnosis[edit | edit source]
Hemophilia B is diagnosed through a blood test that measures the level of factor IX activity. If the factor IX activity is less than 40% of normal, a diagnosis of hemophilia is considered.
Treatment[edit | edit source]
Treatment for Hemophilia B involves replacing the missing factor IX through infusions into a vein. This can be done at a hospital, a hemophilia treatment center, or at home.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD