Hyperthermic perfusion

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Hyperthermic perfusion is a medical procedure used in the treatment of cancer. It involves the circulation of heated chemotherapy drugs in the area of the body where the cancer is located. This method is often used for cancers that are difficult to treat with traditional chemotherapy methods, such as melanoma and peritoneal carcinomatosis.

Procedure[edit | edit source]

The procedure for hyperthermic perfusion involves the surgical removal of visible tumors, followed by the circulation of heated chemotherapy drugs. The heat increases the effectiveness of the drugs, and the circulation ensures that the drugs reach all areas of the tumor. The procedure is usually performed under general anesthesia, and can take several hours to complete.

Benefits[edit | edit source]

Hyperthermic perfusion has several benefits over traditional chemotherapy methods. The heat increases the effectiveness of the drugs, and the circulation ensures that the drugs reach all areas of the tumor. This can result in a higher rate of tumor shrinkage, and can improve the patient's quality of life. In addition, because the drugs are confined to a specific area of the body, there is less risk of systemic side effects.

Risks[edit | edit source]

As with any medical procedure, there are risks associated with hyperthermic perfusion. These can include infection, bleeding, and reactions to the anesthesia. In addition, there is a risk that the heated drugs can damage healthy tissue in the area of the tumor. Patients should discuss these risks with their doctor before deciding to undergo this procedure.

Research[edit | edit source]

Research into hyperthermic perfusion is ongoing, with studies looking at ways to improve the effectiveness of the procedure, and to reduce the associated risks. Current research is focusing on the use of targeted drugs, which can more accurately target the cancer cells, reducing the risk of damage to healthy tissue.

See also[edit | edit source]

Hyperthermic perfusion Resources
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Contributors: Prab R. Tumpati, MD