Idiopathic short stature

Idiopathic short stature
Synonyms	ISS
Pronounce	N/A
Specialty	N/A
Symptoms	Height significantly below average for age and sex
Complications	Psychosocial stress, low self-esteem
Onset	Childhood
Duration	Lifelong
Types	N/A
Causes	Unknown
Risks	Genetic predisposition
Diagnosis	Growth chart analysis, exclusion of other causes
Differential diagnosis	Growth hormone deficiency, Turner syndrome, Chronic illness
Prevention	N/A
Treatment	Growth hormone therapy
Medication	N/A
Prognosis	Variable, often normal adult height
Frequency	Affects approximately 2% of children
Deaths	N/A

Idiopathic Short Stature (ISS) is a term used in the medical field to refer to individuals who are significantly shorter than the average height for their age and sex, without a specific cause being identified. This condition is not associated with any known medical or genetic conditions and is different from short stature caused by growth hormone deficiency or other medical conditions.

Definition

Idiopathic Short Stature is defined as a height that is more than 2 standard deviations below the mean for age and sex, or more than 2 standard deviations below the mid-parental height, without a known cause. This condition is not associated with any known medical or genetic conditions and is different from short stature caused by growth hormone deficiency or other medical conditions.

Causes

The exact cause of Idiopathic Short Stature is unknown. However, it is believed to be a result of a combination of genetic and environmental factors. Some studies suggest that it may be related to a delay in the onset of puberty, while others suggest that it may be related to a slower rate of growth during infancy and early childhood.

Diagnosis

The diagnosis of Idiopathic Short Stature is made based on a thorough medical history and physical examination. Additional tests may be performed to rule out other causes of short stature, such as growth hormone deficiency, Turner syndrome, or other genetic conditions.

Treatment

The treatment for Idiopathic Short Stature is controversial. Some experts believe that treatment is not necessary, as the condition does not affect overall health or lifespan. Others believe that treatment with growth hormone may be beneficial, particularly in individuals who are significantly shorter than their peers and may experience social or psychological difficulties as a result.

See Also

• Growth hormone deficiency
• Turner syndrome
• Short stature

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