Keratosis follicularis
Keratosis follicularis, also known as Darier's disease, is a rare, genetic skin disorder. It is characterized by small, hard bumps on the skin that may be covered with a crust or scaly patch. The bumps are often dark in color and may appear anywhere on the body, but are most commonly found on the chest, back, and scalp.
Symptoms[edit | edit source]
The primary symptom of keratosis follicularis is the presence of small, hard bumps on the skin. These bumps may be covered with a crust or scaly patch and are often dark in color. Other symptoms may include:
Causes[edit | edit source]
Keratosis follicularis is caused by a mutation in the ATP2A2 gene. This gene provides instructions for making a protein that is found in many types of cells, including skin cells. The mutation disrupts the normal function of the protein, leading to the symptoms of keratosis follicularis.
Diagnosis[edit | edit source]
Diagnosis of keratosis follicularis is typically made based on the appearance of the skin. A skin biopsy may be performed to confirm the diagnosis. Genetic testing may also be used to identify the ATP2A2 gene mutation.
Treatment[edit | edit source]
Treatment for keratosis follicularis is aimed at managing symptoms and may include:
Prognosis[edit | edit source]
The prognosis for individuals with keratosis follicularis varies. Some people may experience mild symptoms, while others may have severe skin changes that can affect their quality of life.
See also[edit | edit source]
Keratosis follicularis Resources | ||
---|---|---|
|
|
Translate to: East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD