Multiple endocrine neoplasia type 2A syndrome

A rare, genetic disorder that affects the endocrine glands and causes a type of thyroid cancer called medullary thyroid cancer, pheochromocytoma, and parathyroid gland cancer.

Benign tumors

It may also cause benign (noncancerous) tumors in the parathyroid glands and adrenal glands.

Hormonal disturbance

The affected endocrine glands may make high levels of hormones, which can lead to other medical problems such as high blood pressure and kidney stones.

Skin condition

An itchy skin condition may also occur.

Genetics

Multiple endocrine neoplasia type 2A syndrome is caused by a mutation (change) in a gene called RET.

Other names

Also called MEN2A, MEN2A syndrome, multiple endocrine adenomatosis type 2A, and Sipple syndrome.

Multiple endocrine neoplasia type 2A syndrome Resources
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 This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".