NMS
NMS or Neuroleptic Malignant Syndrome is a life-threatening reaction that can occur in response to neuroleptic or antipsychotic medication. It is characterized by fever, altered mental status, muscle rigidity, and autonomic dysfunction.
Symptoms and Signs[edit | edit source]
The symptoms of NMS are often sudden and severe. They can include:
- High fever
- Sweating
- Unstable blood pressure
- Stupor
- Muscular rigidity
- Autonomic dysregulation
Causes[edit | edit source]
NMS is most commonly caused by an adverse reaction to neuroleptic or antipsychotic drugs. These can include:
Diagnosis[edit | edit source]
Diagnosis of NMS can be challenging, as it can mimic other conditions. It is often diagnosed based on the presence of the characteristic symptoms and a history of recent neuroleptic drug use. Laboratory tests can also be helpful in confirming the diagnosis.
Treatment[edit | edit source]
Treatment of NMS involves discontinuing the offending drug, supportive care, and sometimes the use of medications such as dantrolene or bromocriptine.
Prognosis[edit | edit source]
With prompt recognition and treatment, the prognosis for NMS is generally good. However, it can be fatal if not treated promptly.
See Also[edit | edit source]
References[edit | edit source]
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