Nucleus pulposus

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Nucleus pulposus is the inner core of the vertebral disc. It contains a large amount of water, proteins, and sugars, which give it a gel-like consistency. The nucleus pulposus acts as a shock absorber, distributing forces evenly across the disc.

Structure[edit | edit source]

The nucleus pulposus is located in the center of the vertebral disc and is surrounded by the annulus fibrosus. It is composed of water, collagen, and proteoglycans. The high water content gives the nucleus pulposus its gel-like consistency and allows it to resist compression. The collagen and proteoglycans provide structural support.

Function[edit | edit source]

The primary function of the nucleus pulposus is to distribute forces evenly across the disc. When pressure is applied to the spine, the water within the nucleus pulposus moves in a way that helps to evenly distribute the load. This helps to prevent damage to the disc and surrounding structures.

Clinical significance[edit | edit source]

Damage or degeneration of the nucleus pulposus can lead to a number of conditions, including disc herniation, disc degeneration, and spinal stenosis. These conditions can cause pain, numbness, and other symptoms.

See also[edit | edit source]

References[edit | edit source]

Nucleus pulposus Resources
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Contributors: Prab R. Tumpati, MD