Panipenem
Panipenem is a carbapenem antibiotic that is often used in combination with betamipron, a renal dehydropeptidase inhibitor. This combination is used to prevent the degradation of panipenem in the kidneys. Panipenem/betamipron is marketed under the brand name Carbapenem in Japan.
Medical uses[edit | edit source]
Panipenem is used to treat a variety of bacterial infections, including those caused by Gram-positive bacteria and Gram-negative bacteria. It is particularly effective against Pseudomonas aeruginosa, Enterobacteriaceae, and Staphylococcus aureus.
Pharmacology[edit | edit source]
Panipenem works by inhibiting the synthesis of the bacterial cell wall, leading to cell death. It is a broad-spectrum antibiotic, meaning it is effective against a wide range of bacteria.
Side effects[edit | edit source]
Common side effects of panipenem include nausea, vomiting, diarrhea, and rash. In rare cases, it can cause more serious side effects such as anaphylaxis, a severe allergic reaction.
History[edit | edit source]
Panipenem was first approved for medical use in Japan in 1993. It is not currently approved for use in the United States.
See also[edit | edit source]
Panipenem Resources | ||
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