Pivagabine

Pivagabine is a pharmaceutical drug that was under development for the treatment of anxiety but was discontinued. It is a pyridinyl derivative and has anxiolytic effects.

Pharmacology[edit | edit source]

Pivagabine acts as a GABA reuptake inhibitor, which means it increases the levels of the neurotransmitter GABA in the brain. GABA is the main inhibitory neurotransmitter in the brain and is involved in reducing neuronal excitability. By increasing the levels of GABA, pivagabine can reduce anxiety.

Clinical Trials[edit | edit source]

Pivagabine was tested in several clinical trials for its potential use in treating anxiety. However, the drug was discontinued and is not currently available for use.

Side Effects[edit | edit source]

Like all drugs, pivagabine has potential side effects. These can include dizziness, nausea, and fatigue. However, as the drug was discontinued, a full profile of its side effects is not available.

See Also[edit | edit source]

Pivagabine Resources
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