Pleurothotonus

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Pleurothotonus (also known as Pisa syndrome) is a rare neurological disorder characterized by a sustained, involuntary muscle contraction that leads to an abnormal posture of the body. This condition is often associated with Parkinson's disease and other neurodegenerative diseases, as well as the use of certain antipsychotic drugs.

Symptoms[edit | edit source]

The primary symptom of Pleurothotonus is a sustained, involuntary muscle contraction that leads to an abnormal posture of the body. This can include a lateral (sideways) bending of the body and neck, and a rotation of the trunk. The symptoms can be severe enough to affect balance and mobility, and can cause significant discomfort and disability.

Causes[edit | edit source]

Pleurothotonus is often associated with Parkinson's disease and other neurodegenerative diseases. It can also be caused by the use of certain antipsychotic drugs, particularly those that block the action of dopamine, a neurotransmitter that plays a key role in the control of movement.

Diagnosis[edit | edit source]

Diagnosis of Pleurothotonus is based on a clinical examination and the patient's medical history. Imaging tests such as MRI or CT scan may be used to rule out other conditions that can cause similar symptoms.

Treatment[edit | edit source]

Treatment of Pleurothotonus is primarily aimed at managing the symptoms and improving the patient's quality of life. This can include the use of medications to control muscle contractions, physical therapy to improve mobility and balance, and in some cases, surgery to correct the abnormal posture.

See also[edit | edit source]

Pleurothotonus Resources
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Contributors: Prab R. Tumpati, MD