Secondary syphilis

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Secondary syphilis is the second stage of syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum. This stage typically starts with the development of a skin rash and mucous membrane lesions, weeks to months after the initial exposure.

Signs and symptoms[edit | edit source]

The most common symptom of secondary syphilis is a non-itchy rash that appears on the palms of the hands and soles of the feet. Other symptoms may include fever, swollen lymph glands, sore throat, patchy hair loss, headaches, weight loss, muscle aches, and fatigue.

Causes[edit | edit source]

Secondary syphilis is caused by the bacterium Treponema pallidum, which is usually transmitted through sexual contact. The bacteria can also be passed from mother to child during pregnancy.

Diagnosis[edit | edit source]

The diagnosis of secondary syphilis is usually made based on the presence of symptoms and a positive blood test for syphilis. The most commonly used tests are the Venereal Disease Research Laboratory (VDRL) test and the Rapid Plasma Reagin (RPR) test.

Treatment[edit | edit source]

The treatment for secondary syphilis is usually a single dose of penicillin given by injection. People who are allergic to penicillin can be treated with other antibiotics.

Prognosis[edit | edit source]

With early diagnosis and treatment, the prognosis for secondary syphilis is good. However, if left untreated, the disease can progress to the third stage, known as tertiary syphilis, which can cause serious health problems.

Prevention[edit | edit source]

The best way to prevent secondary syphilis is to avoid sexual contact with infected individuals, use condoms during sexual activity, and get regular testing for sexually transmitted infections.

See also[edit | edit source]

Secondary syphilis Resources
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Contributors: Prab R. Tumpati, MD