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Wilkinson's Syndrome is a rare medical condition characterized by hyperhidrosis (excessive sweating), flushing, and mitral valve prolapse. The syndrome was first described by Dr. Wilkinson in 1969.

Symptoms

The primary symptoms of Wilkinson's Syndrome include:

• Hyperhidrosis: This is a condition where a person sweats excessively and unpredictably. People with hyperhidrosis may sweat even when the temperature is cool or when they are at rest.
• Flushing: This is a temporary redness of the face and neck caused by dilation of the blood capillaries.
• Mitral valve prolapse: This is a condition in which the two valve flaps of the mitral valve do not close smoothly or evenly, but bulge (prolapse) upward into the left atrium.

Causes

The exact cause of Wilkinson's Syndrome is unknown. However, it is believed to be a genetic disorder, as it often runs in families.

Diagnosis

Diagnosis of Wilkinson's Syndrome is based on the presence of the three primary symptoms. Additional tests may be conducted to confirm the diagnosis, such as:

• Echocardiogram: This test uses sound waves to produce images of the heart, allowing the doctor to see if the mitral valve is prolapsing.
• Sweat test: This test measures the amount of sweat produced, and can confirm the presence of hyperhidrosis.

Treatment

Treatment for Wilkinson's Syndrome is focused on managing the symptoms. This may include:

• Antiperspirants: Prescription-strength antiperspirants may be used to control excessive sweating.
• Beta blockers: These medications can help manage symptoms of mitral valve prolapse.
• Surgery: In severe cases, surgery may be required to repair the mitral valve.

See also

• Hyperhidrosis
• Mitral valve prolapse
• Flushing (physiology)

References

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