Sulfoxone

Sulfoxone is a sulfone antibiotic used in the treatment of leprosy and tuberculosis. It is a synthetic compound that was first introduced in the 1940s. Sulfoxone is also known by its chemical name, diaminodiphenyl sulfone (DDS).

History

Sulfoxone was first synthesized in the 1940s as part of a broader effort to develop effective treatments for bacterial infections. It was initially used to treat tuberculosis, but was later found to be effective against leprosy as well.

Mechanism of Action

Sulfoxone works by inhibiting the synthesis of folic acid in bacteria, which is necessary for their growth and reproduction. It is a bacteriostatic agent, meaning it prevents bacteria from multiplying without necessarily killing them.

Uses

Sulfoxone is primarily used in the treatment of leprosy and tuberculosis. It is often used in combination with other drugs to prevent the development of drug resistance.

Side Effects

Common side effects of sulfoxone include nausea, vomiting, headache, and dizziness. In rare cases, it can cause serious side effects such as anemia, hepatitis, and psychosis.

See Also

• Dapsone
• Rifampicin
• Isoniazid

References

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