Trophoblastic
Trophoblastic Disease
Trophoblastic disease is a group of rare tumors that involve abnormal growth of cells inside a woman's uterus. Trophoblastic disease almost always occurs as a result of pregnancy. The two main types of trophoblastic disease are Hydatidiform Mole and Choriocarcinoma.
Types of Trophoblastic Disease[edit | edit source]
Hydatidiform Mole[edit | edit source]
A Hydatidiform Mole is a type of gestational trophoblastic disease that occurs when the fertilization of an egg by a sperm results in an abnormal pregnancy. There are two types of hydatidiform moles: complete and partial.
Complete Hydatidiform Mole[edit | edit source]
A complete hydatidiform mole occurs when an empty egg is fertilized by one or two sperm, and all the genetic material is from the father.
Partial Hydatidiform Mole[edit | edit source]
A partial hydatidiform mole occurs when a normal egg is fertilized by two sperm or by one sperm that duplicates itself, resulting in an embryo with too many chromosomes.
Choriocarcinoma[edit | edit source]
Choriocarcinoma is a rare and aggressive form of cancer that occurs in a woman's uterus (womb). The disease is a type of gestational trophoblastic disease (GTD).
Symptoms[edit | edit source]
The symptoms of trophoblastic disease can vary depending on the type. Common symptoms include vaginal bleeding, severe nausea and vomiting, and early preeclampsia.
Diagnosis[edit | edit source]
Trophoblastic disease can be diagnosed through a series of tests, including a pregnancy test, ultrasound, and blood tests to measure the level of human chorionic gonadotropin (hCG).
Treatment[edit | edit source]
Treatment for trophoblastic disease depends on the type of disease, the patient's age, and the patient's overall health. Treatment options include surgery, chemotherapy, and radiation therapy.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD