Typical antipsychotic
Typical antipsychotic is a term that refers to the first generation of antipsychotic drugs used primarily to treat psychosis. These drugs are also known as first-generation antipsychotics, conventional antipsychotics, or major tranquilizers.
History[edit | edit source]
The first typical antipsychotic, chlorpromazine, was discovered in the 1950s. This discovery marked a significant advancement in the treatment of psychosis and has since led to the development of many other typical antipsychotics.
Mechanism of Action[edit | edit source]
Typical antipsychotics work by blocking dopamine receptors in the brain, specifically the D2 receptors. This helps to reduce the overactivity of dopamine, which is thought to be a contributing factor in conditions such as schizophrenia and bipolar disorder.
Uses[edit | edit source]
Typical antipsychotics are used to treat a variety of conditions, including:
Side Effects[edit | edit source]
Like all medications, typical antipsychotics can cause side effects. These may include:
- Extrapyramidal symptoms (EPS), such as tremors, slurred speech, and akathisia
- Tardive dyskinesia, a condition characterized by involuntary movements
- Neuroleptic malignant syndrome, a rare but potentially life-threatening reaction to antipsychotic drugs
- Sedation
- Weight gain
Examples[edit | edit source]
Examples of typical antipsychotics include:
See Also[edit | edit source]
Typical antipsychotic Resources | ||
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