File:180-TALEffectors TALEN.png

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Summary[edit]

Summary
Description Space-filling drawing of an engineered TAL effector/nuclease bound to double-helical DNA. TALE proteins contain a series of alpha-helical hairpin domains, each of which binds an individual DNA base, so that the protein recognizes a long, very specific DNA sequence. This engineered construct attaches the specific FOK1 nuclease to one end of the TALE protein, and when two copies bind as a dimer the nuclease cleaves both strands of the DNA. Drawn by David Goodsell from PDB files 1FOK (nuclease/DNA) and 3UGM (TALE/DNA).
Source Wikimedia Commons file page
Author David Goodsell
Permission See original Commons license details.

Licensing[edit]

Creative Commons Attribution 3.0 Unported (CC BY 3.0)

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Official license: CC BY 3.0

License page: CC BY 3.0

Original attribution and file history: Wikimedia Commons

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current02:13, 7 June 2026Thumbnail for version as of 02:13, 7 June 20261,655 × 706 (782 KB)Maintenance script (talk | contribs)== Summary == Importing file

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