File:A-dynamin-1--dynamin-3--and-clathrin-independent-pathway-of-synaptic-vesicle-recycling-mediated-by-elife01621f013.jpg

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Summary[edit]

Summary
Description At left is CME. At right is bulk endocytosis followed by fragmentation of bulk endosomes to generate new vesicles. As membranes of bulk endosomes are expected to be enriched in SV proteins, functional SVs may be generated by this mechanism. The uncoated invaginations occurring near active zones and described by Watanabe et al. (2013a and 2013b) may represent a form of this type of clathrin-independent endocytosis. At subsequent exo–endocytic cycles, however, CME may help reestablish SV reformation with high fidelitiy.
Source Wikimedia Commons file page
Author Wu Y, O'Toole E, Girard M, Ritter B, Messa M, Liu X, McPherson P, Ferguson S, De Camilli P
Permission See original Commons license details.

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