File:ABCG2 with plasma membrane.jpg

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Summary[edit]

Summary
Description The ABCG2 channel is a human multidrug transporter. Cholesterol molecules play an integral role in the function of the protein. The gap on the intracellular side is the binding pocket where drugs first bind. The intracellular loops also possess nucleotide-binding pockets that allow ATP hydrolysis to pump drugs to the extracellular environment.

Taylor et al., “Structure of the Human Multidrug Transporter ABCG2.” Visualizations were created using the Chimera program.

UCSF Chimera--a visualization system for exploratory research and analysis. Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, Meng EC, Ferrin TE. J Comput Chem. 2004 Oct;25(13):1605-12.
Source Wikimedia Commons file page
Author DSchlink15
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current02:06, 7 June 2026Thumbnail for version as of 02:06, 7 June 2026586 × 668 (92 KB)Maintenance script (talk | contribs)== Summary == Importing file

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