File:A profile HMM modelling a multiple sequence alignment.png

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A_profile_HMM_modelling_a_multiple_sequence_alignment.png (800 × 421 pixels, file size: 205 KB, MIME type: image/png)

Summary[edit]

Summary
Description The boxes in yellow are the match states (M). In the M state the probability distribution is the frequency of the amino acids in that position. The row of diamond shaped states are insert states (I) which are used to model highly variable regions in the alignment. The circular states are delete states (D). These are called silent states since they do not match any residues, and they are there merely to make it possible to jump over one or more columns in the alignment.The final probabilistic model conveys the estimation of the observed frequencies of the amino acids in each position, as well as the transitions between the amino acids derived from the observed occupancy of each position in a multiple sequence alignment.[1]
Source Wikimedia Commons
Author EMBL-EBI Train Online
Permission See Commons

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current01:21, 2 June 2026Thumbnail for version as of 01:21, 2 June 2026800 × 421 (205 KB)Maintenance script (talk | contribs)== Summary == Importing file

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