File:HCR-FISH visualization of collagen expression in P. waltl.jpg
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Summary[edit]
| Summary | |
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| Description | Top: Black and white bright-field microscopic view of four salamanders (Pleurodeles waltl) at developmental stages 35-37. Specimens 1 and 2 are captured ventrally, whereas specimens 3 and 4 are imaged dorsally. Among these, specimens 1, 3, and 4 are leucistic mutants, characterized by a knocked-out pigmentation gene, while specimen 2 is a wild-type, exhibiting no genetic mutations.
Bottom: The bottom panel illustrates the collagen expression patterns (CO2A1 gene) in these same salamanders, employing Hybridization Chain Reaction RNA Fluorescence In Situ Hybridization (HCR RNA-FISH) technology. The fluorescent visualization predominantly highlights the skeletal areas where collagen is abundantly present. Nonetheless, collagen expression is also observable in other regions, including the gills and on a distinct patch on top of the head. The image was captured by Lennart Rikk from the Regenerative Immunology Lab (https://leighnd.github.io/) using Leica M205 FCA microscope. |
| Source | Wikimedia Commons file page |
| Author | Yodalr |
| Permission | See original Commons license details. |
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Creative Commons Attribution 4.0 International (CC BY 4.0)
This file is licensed under the Creative Commons Attribution 4.0 International license.
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Official license: CC BY 4.0
License page: CC BY 4.0
Original attribution and file history: Wikimedia Commons
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| current | 03:20, 5 June 2026 | | 2,048 × 3,624 (3.06 MB) | Maintenance script (talk | contribs) | == Summary == Importing file |
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