File:TRPC5 Chemo.jpg
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Summary[edit]
| Summary | |
|---|---|
| Description | Two distinct TRPC5 mediated the cancer drug resistance. (a) TRPC5 overexpression activates the transcription factor NFATC3 Ca2+ signaling pathway, leading to p-gp overexpression. Moreover, the overexpressed p-gp expels chemotherapeutic drugs triggering chemoresistance. (b) Chemoresistant breast cancer cells overexpressing TRPC5 transfer channel units to chemo sensitive recipient cells via extracellular vesicles (EV), leading to the development of TRPC5-mediated chemoresistance in these cells. |
| Source | Wikimedia Commons file page |
| Author | Mayar Soussi, Alice Hasselsweiller, and Dimitra Gkika |
| Permission | See original Commons license details. |
Licensing[edit]
Creative Commons Attribution 4.0 International (CC BY 4.0)
This file is licensed under the Creative Commons Attribution 4.0 International license.
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Official license: CC BY 4.0
License page: CC BY 4.0
Original attribution and file history: Wikimedia Commons
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 22:27, 8 June 2026 | | 1,079 × 1,510 (293 KB) | Maintenance script (talk | contribs) | == Summary == Importing file |
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