File:Villous adenoma of the sigmoid colon, gross pathology.jpg

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Summary
Description	Another case of villous adenoma of the transverse colon, this one more discrete and polyp-like than the case above. Although it had a semi-decent stalk, it was still far too large for safe removal by endoscopy, so the surgeon was called in to do a segmental resection of the colon. Prior to photographing, the specimen was pinned out in formalin and fixed overnight. The pink color in the center of the mass indicates that the formalin did not penetrate the whole lesion. Shame on me for being chintzy with the formalin! Note how the surface texture of the villous adenoma differs markedly from that of the surrounding colonic mucosa. The photo above was shot with a Nikon D100 digital SLR with Sigma 50mm f/2.8 macro lens. I stopped the diaphragm way down (about f/22) to bring as much of this very three-dimensional lesion as possible into focus. In Photoshop, I resized the image for Web display, sharpened the 'L' channel in Lab mode, and used the Levels command to brighten it a bit. Since many Web users now have flat-panel displays (not as bright as CRTs) and use their monitors in full room lighting, I like to brighten up pictures more than I would for an image that was meant for projection in a properly darkened lecture hall. Photography by Ed Uthman, MD. Public domain. Posted 27 May 01; updated 20 Feb 05
Source	Wikimedia Commons file page
Author	See Wikimedia Commons file page
Permission	See original Commons license details.

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	Date/Time	Thumbnail	Dimensions	User	Comment
current	03:34, 5 June 2026		650 × 432 (64 KB)	Maintenance script (talk \| contribs)	== Summary == Importing file

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Camera manufacturer	NIKON CORPORATION
Camera model	NIKON D100
Exposure time	1/30 sec (0.033333333333333)
F Number	f/8
Date and time of data generation	11:10, 11 February 2004
Lens focal length	50 mm
Orientation	Normal
Horizontal resolution	300 dpi
Vertical resolution	300 dpi
Software used	Adobe Photoshop 7.0
File change date and time	08:36, 20 February 2005
Y and C positioning	Co-sited
Exposure Program	Aperture priority
Exif version	2.2
Date and time of digitizing	11:10, 11 February 2004
Meaning of each component	Y Cb Cr does not exist
Image compression mode	4
APEX exposure bias	0
Maximum land aperture	3 APEX (f/2.83)
Metering mode	Spot
Light source	Tungsten (incandescent light)
Flash	Flash did not fire
DateTime subseconds	10
DateTimeOriginal subseconds	10
DateTimeDigitized subseconds	10
Supported Flashpix version	1
Color space	Uncalibrated
Sensing method	One-chip color area sensor
File source	Digital still camera
Scene type	A directly photographed image
Custom image processing	Custom process
Exposure mode	Auto exposure
White balance	Manual white balance
Digital zoom ratio	1
Focal length in 35 mm film	75 mm
Scene capture type	Standard
Scene control	None
Contrast	Normal
Saturation	Normal
Sharpness	Normal
Subject distance range	Unknown
IIM version	2