Dexmedetomidine
(Redirected from PRECEDEX)
Dexmedetomidine is a sedative medication used by healthcare professionals to reduce pain and anxiety. It is often used in the intensive care unit (ICU) to sedate patients who are on a ventilator. Dexmedetomidine works by slowing activity in the brain and nervous system.
Uses[edit | edit source]
Dexmedetomidine is used in a hospital setting for:
- Sedation in the intensive care unit (ICU)
- Procedural sedation (for example, during a bronchoscopy, endoscopy, or other diagnostic procedures)
- As an adjunct to anesthesia
Side Effects[edit | edit source]
Like all medications, dexmedetomidine can cause side effects. These may include:
- Low blood pressure (hypotension)
- Slow heart rate (bradycardia)
- Dry mouth
- Nausea
- Fever
Contraindications[edit | edit source]
Dexmedetomidine should not be used in people with:
- Severe heart block, unless they have a functioning pacemaker
- Allergy to dexmedetomidine or any of its components
Interactions[edit | edit source]
Dexmedetomidine can interact with other medications, including:
Pharmacology[edit | edit source]
Dexmedetomidine is a selective alpha-2 adrenergic agonist. This means it binds to alpha-2 receptors in the brain, leading to a decrease in sympathetic activity and an increase in parasympathetic activity. This results in a decrease in heart rate and blood pressure.
History[edit | edit source]
Dexmedetomidine was first approved by the Food and Drug Administration (FDA) in 1999.
See Also[edit | edit source]
Dexmedetomidine Resources | ||
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