Alexander Niculescu

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Alexander Niculescu is a renowned psychiatrist and molecular biologist known for his significant contributions to the field of psychiatric genetics. He is currently a Professor of Psychiatry at Indiana University School of Medicine, where he leads a research team focused on understanding the genetic and molecular basis of mood disorders and suicide.

Early Life and Education[edit | edit source]

Niculescu was born and raised in Romania. He moved to the United States for his higher education, where he earned his M.D. from the University of Medicine and Pharmacy of Timișoara and his Ph.D. in Genetics from the University of California, Los Angeles.

Career[edit | edit source]

Niculescu's research primarily focuses on the genetic and molecular mechanisms underlying psychiatric disorders. His work has led to the development of several novel diagnostic and therapeutic approaches for mood disorders and suicide. He has published numerous research articles in prestigious scientific journals and has received several awards for his contributions to the field.

Research[edit | edit source]

Niculescu's research team uses a comprehensive approach that combines genomic and phenotypic data to identify genes associated with psychiatric disorders. His team has developed a method called Convergent Functional Genomics (CFG) that integrates genetic, gene expression, and bioinformatic data to identify and prioritize genes for further study.

Contributions[edit | edit source]

Niculescu's work has significantly advanced our understanding of the genetic basis of mood disorders and suicide. His research has led to the development of several novel diagnostic tools and treatments, including a blood test for suicide risk and a new class of drugs for treating mood disorders.

Awards and Recognition[edit | edit source]

Niculescu has received numerous awards and recognition for his work, including the NARSAD Young Investigator Award and the American Psychiatric Association's Kempf Fund Award for Research Development in Psychiatric Illness.


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Contributors: Prab R. Tumpati, MD