Biochemical pathway

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Biochemical Pathway

A biochemical pathway is a series of chemical reactions that occur within a cell. In a biochemical pathway, the product of one reaction serves as the substrate for the next reaction. The reactions are catalyzed by enzymes, which are proteins that speed up chemical reactions in the body.

Biochemical pathways are essential for many biological processes, including metabolic processes, cell signaling, and gene expression. They are also involved in the synthesis and breakdown of molecules such as proteins, lipids, and nucleic acids.

Types of Biochemical Pathways[edit | edit source]

There are two main types of biochemical pathways: anabolic pathways and catabolic pathways.

Anabolic pathways are those that involve the synthesis of complex molecules from simpler ones. These pathways require energy, which is usually provided by ATP. Examples of anabolic pathways include protein synthesis and photosynthesis.

Catabolic pathways are those that involve the breakdown of complex molecules into simpler ones. These pathways release energy, which can be used to fuel anabolic pathways. Examples of catabolic pathways include glycolysis and cellular respiration.

Regulation of Biochemical Pathways[edit | edit source]

Biochemical pathways are tightly regulated by the cell. This is achieved through a variety of mechanisms, including enzyme inhibition, feedback inhibition, and allosteric regulation. These mechanisms ensure that the cell maintains a balance between the synthesis and breakdown of molecules, and that energy is used efficiently.

Clinical Significance[edit | edit source]

Abnormalities in biochemical pathways can lead to a variety of diseases. For example, defects in the urea cycle, a biochemical pathway that removes excess nitrogen from the body, can lead to urea cycle disorders. Similarly, abnormalities in the glycolytic pathway, which breaks down glucose to produce energy, can lead to diabetes mellitus.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD