CDV3 (gene)

CDV3 is a gene that in humans is encoded by the CDV3 homolog (CDV3) gene. The CDV3 gene is located on chromosome 3 (3q26.31) and spans approximately 16.5 kilobases. The gene is composed of 10 exons and encodes a protein of 243 amino acids.

Function

The CDV3 gene is involved in the regulation of cell division and cell cycle. It is also associated with the cilia and flagella assembly. The protein encoded by this gene is a component of the dynein regulatory complex (DRC), which is a key regulator of ciliary and flagellar movement.

Clinical significance

Mutations in the CDV3 gene have been associated with primary ciliary dyskinesia (PCD), a rare genetic disorder characterized by chronic respiratory tract infections, abnormally positioned internal organs, and the inability to have children.

Research

Research on the CDV3 gene is ongoing, with studies focusing on its role in cell division and its association with primary ciliary dyskinesia. Understanding the function of the CDV3 gene may lead to new treatments for diseases associated with cell division abnormalities and ciliary dysfunction.

See also

• Gene
• Chromosome 3
• Cell division
• Cell cycle
• Cilia
• Flagella
• Dynein
• Primary ciliary dyskinesia

References

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