Case definition

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Case Definition[edit | edit source]

A case definition is a set of criteria used to identify and classify cases of a particular disease, condition, or event. It is an essential tool in epidemiology and public health surveillance, helping to standardize the identification and reporting of cases for monitoring and control purposes.

Components of a Case Definition[edit | edit source]

A typical case definition includes the following components:

1. Clinical Criteria: These are the signs and symptoms that a person must exhibit to be considered a case. These criteria are often based on medical knowledge and may include specific laboratory test results.

2. Epidemiological Criteria: These criteria define the time, place, and person aspects of the case. They help to determine the context in which the case occurred and identify any common exposures or risk factors.

3. Laboratory Criteria: In some cases, laboratory confirmation is required to meet the case definition. This may involve specific tests or procedures to detect the presence of a pathogen or other biological marker.

4. Case Classification: Cases may be classified as confirmed, probable, or suspected based on the level of evidence available. This classification helps to standardize reporting and analysis.

Importance of Case Definitions[edit | edit source]

Case definitions play a crucial role in disease surveillance, outbreak investigation, and research. They enable public health authorities to:

  • Monitor disease trends and patterns over time.
  • Detect outbreaks and clusters of cases.
  • Evaluate the effectiveness of control measures.
  • Compare data across different regions and time periods.

Examples of Case Definitions[edit | edit source]

  • Influenza: A case of influenza may be defined as a person with acute onset of respiratory illness and fever, with laboratory confirmation of influenza virus infection.
  • Tuberculosis: A case of tuberculosis is typically defined as a person with clinical symptoms consistent with TB, along with positive laboratory tests for Mycobacterium tuberculosis.

For more information on specific case definitions, refer to the Epidemiology and Public Health Surveillance articles.


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Contributors: Prab R. Tumpati, MD