Fluoxetine hydrochloride

From WikiMD's Food, Medicine & Wellness Encyclopedia

Fluoxetine Hydrochloride is a type of antidepressant medication that belongs to the class of drugs known as Selective Serotonin Reuptake Inhibitors (SSRIs). It is used to treat a variety of mental health conditions, including Major Depressive Disorder (MDD), Obsessive-Compulsive Disorder (OCD), Panic Disorder, and Bulimia Nervosa.

Pharmacology[edit | edit source]

Fluoxetine Hydrochloride works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance. It does this by inhibiting the reuptake of serotonin in the brain, thus increasing the concentration of serotonin in the synaptic cleft.

Uses[edit | edit source]

Fluoxetine Hydrochloride is primarily used to treat Major Depressive Disorder (MDD), but it is also effective in treating other mental health conditions. These include Obsessive-Compulsive Disorder (OCD), Panic Disorder, Bulimia Nervosa, and Premenstrual Dysphoric Disorder (PMDD).

Side Effects[edit | edit source]

Like all medications, Fluoxetine Hydrochloride can cause side effects. Common side effects include nausea, upset stomach, diarrhea, dry mouth, sleep problems, and weight changes. More serious side effects can include serotonin syndrome, abnormal bleeding, and changes in sexual desire or ability.

Precautions[edit | edit source]

Before taking Fluoxetine Hydrochloride, it is important to inform your doctor if you have a history of allergies, liver disease, kidney disease, heart problems, or a history of suicidal thoughts. It is also important to avoid alcohol while taking this medication, as it can increase the risk of side effects.

Interactions[edit | edit source]

Fluoxetine Hydrochloride can interact with a number of other medications, including other antidepressants, MAO inhibitors, pimozide, thioridazine, and St. John's wort. It is important to inform your doctor of all medications you are currently taking before starting Fluoxetine Hydrochloride.


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Contributors: Prab R. Tumpati, MD