Metaplastic carcinoma

From WikiMD's Food, Medicine & Wellness Encyclopedia

Metaplastic carcinoma is a rare type of breast cancer that accounts for less than 1% of all breast cancer cases. It is characterized by the presence of both epithelial and mesenchymal components in the tumor tissue. This type of cancer is known for its aggressive behavior and poor prognosis compared to other types of breast cancer.

Symptoms[edit | edit source]

Metaplastic carcinoma may present with symptoms similar to other types of breast cancer, such as a lump or mass in the breast, changes in the size or shape of the breast, skin changes on the breast, nipple discharge, or pain in the breast or nipple.

Diagnosis[edit | edit source]

Diagnosis of metaplastic carcinoma is typically made through a combination of imaging tests, such as mammography or ultrasound, and a biopsy of the suspicious tissue. The biopsy will reveal the presence of both epithelial and mesenchymal components in the tumor tissue, confirming the diagnosis of metaplastic carcinoma.

Treatment[edit | edit source]

Treatment for metaplastic carcinoma usually involves a combination of surgery, chemotherapy, and radiation therapy. Surgery is often the first line of treatment and may involve a lumpectomy or mastectomy, depending on the size and location of the tumor. Chemotherapy and radiation therapy may be used before or after surgery to help shrink the tumor and reduce the risk of recurrence.

Prognosis[edit | edit source]

Metaplastic carcinoma is known to have a poorer prognosis compared to other types of breast cancer. The aggressive nature of this type of cancer can make it more difficult to treat, and the risk of recurrence is higher. However, the prognosis can vary depending on the stage of the cancer at the time of diagnosis and the individual characteristics of the tumor.

Prevention[edit | edit source]

There are no specific guidelines for preventing metaplastic carcinoma, as the exact cause of this type of cancer is not well understood. However, maintaining a healthy lifestyle, including regular exercise, a balanced diet, and avoiding known risk factors for breast cancer, such as smoking and excessive alcohol consumption, may help reduce the risk of developing any type of breast cancer.


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Contributors: Prab R. Tumpati, MD